Nanoprobes are microscopic machines that inhabit a Borg's body, bloodstream, and many cybernetic implants. The probes perform the function of maintaining the Borg cybernetic systems, as well as repairing damage to the organic parts of a Borg. They generate new technology inside a Borg when needed, as well as protecting them from many forms of disease. Borg nanoprobes, each about the size of a human red blood cell, travel through the victim's bloodstream and latch on to individual cells. The nanoprobes rewrite the cellular DNA, altering the victim's biochemistry, and eventually form larger, more complicated structures and networks within the body such as electrical pathways, processing and data-storage nodes, and ultimately prosthetic devices that spring forth from the skin. In "Mortal Coil", Seven of Nine states that the Borg assimilated the nanoprobe technology from "Species 149". In addition, the nanoprobes work to maintain and repair their host's mechanical and biological components on a microscopic level, allowing regenerative capabilities.
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