Thrax assumes leadership of a gang of sweat germs and launches an attack on the mucus dam in Frank's nose, causing a runny nose, nearly expelling Ozzy and Drix before Frank inhales them back into the sinuses. As they continue their investigation, Drix hears Phlegmming accusing Ozzy of having the worst record in Frank's body, and he doesn't want a repeat of the same while Frank is currently planning a trip to a chicken wing festival in Buffalo, New York. When he asks Ozzy about having a record, Ozzy reveals to Drix that two years prior, during a science fair at Shane's school, he caused Frank to publicly vomit on Shane's science and P. E. teacher, Mrs. Boyd (Molly Shannon), after seeing a deadly virus on an oyster Frank ate earlier after observing another student's oyster display, due to a boy directing people's attention towards Frank moments before he vomited. The story ran in the newspaper the next day, resulting in Frank, Shane, and Mrs. Boyd becoming the town laughingstock overnight. Frank was also fired from his job at the pea soup factory by his manager and supervisor after the incident embarrassed them, and Mrs. Boyd, after seeing her three kids get mercilessly bullied because of the incident (her daughter Shirley had to change schools as a result and her younger sons Ralph and Chuck have had to continue to endure it), took out a 200-yard restraining order on him to prevent further humiliation by him. His brother, Shane's uncle Bob (Chris Elliott), later helped him get a job at the zoo, where Frank still gets zero respect. Ozzy, in turn, was then suspended from his job working in the stomach and kidneys and then demoted to patrol duty in the mouth for excessive use of unnecessary force due to no one else seeing the virus before he induced Frank to vomit. He tells Drix that since that day he continuously wonders if what he did was right. Drix, in turn, assures Ozzy that he was justified in his actions as raw oysters are frequent breeding grounds for potentially dangerous bacteria of any kind.
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